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Villarreal-Barragan is an experienced clinical operations leader with expertise in early phase oncology and innovative therapeutic modalities.
March 2, 2026
By: Charlie Sternberg
3T Biosciences, an immunotherapy company, has appointed Rebeca Villarreal-Barragan, MBA, as head of clinical operations where she will lead all aspects of clinical operations as the company advances its pipeline of T-cell receptor (TCR)-based therapeutics for solid tumors.
“Rebeca brings a strong track record of building and leading clinical operations in both established biopharma organizations and emerging biotechnology companies,” said Behzad Kharabi, M.D., Chief Medical Officer of 3T Biosciences. “Her pragmatic, quality-focused approach and experience delivering complex early phase clinical trials will be an important asset as we progress our pipeline of TCR-based therapeutics for solid tumors into the clinic, and ultimately to patients in need.”
Villarreal-Barragan is an experienced clinical operations leader with expertise in early phase oncology and innovative therapeutic modalities. She has led global clinical trial delivery across first-in-human and complex, biomarker-driven studies, working closely with clinical development, regulatory, CMC, translational, and preclinical teams to ensure integrated and execution-ready development strategies.
Prior to joining 3T, Villarreal-Barragan held clinical operations leadership roles at Gilead Sciences and Kite Pharma, as well as at biotechnology start-ups including T-Knife Therapeutics and Achilles Therapeutics. Across these roles, she built fit-for-purpose clinical operations, led CRO and vendor oversight, and supported inspection-ready execution in fast-moving, resource-constrained environments.
She holds an MBA from the University of Buckingham in England, and a bachelor’s degree in biotechnology from the Monterrey Institute of Technology and Higher Education in Mexico.
“Clinical execution and aligning clinical delivery with scientific strategy, timelines, and capital efficiency are critical to delivering 3T’s breakthrough medicines for the treatment of solid tumors to patients,” said Villarreal-Barragan. “I’m excited to join the team and to work across functions to support the execution of high-quality clinical trials.”
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